Cell Culture & Drug Transporter Assays

Cell culture reagents, ABC transporter vesicle kits and validated human renal cell lines for preclinical drug research – available exclusively through SeamlessBio for the DACH region.

Our portfolio covers enzymatic cell culture reagents, primary cell isolation solutions, ABC transporter vesicle kits, and human renal cell lines (ciPTEC) from Cell4Pharma.

Cell Culture Reagents

Papain solution as a plant-based, sustainable alternative to trypsin for gentle cell dissociation, and Lymphobio for reliable PBMC isolation by density gradient centrifugation – ready-to-use, sterile, and long-term stable.

ABC Transporter Vesicle Kits (Cell4Pharma) Normal: Inside-out membrane vesicles isolated from HEK293 cells for the detection of ATP-dependent substrate transport. Validated for MRP1, MRP2, MRP3, MRP4, MRP5, MRP8, BCRP, BSEP, Pgp, and control vesicles. Guaranteed ATP/AMP ratios ≥5 to ≥20. Compatible with radiolabel, fluorescent, and LC-MS detection. Compliant with FDA (2017) and EMA (2013) DDI guidance.

ciPTEC – Human Renal Cell Lines (Cell4Pharma) 

Conditionally immortalized proximal tubule epithelial cells (ciPTEC, ciPTEC-OAT1, ciPTEC-OAT3) with stable expression of functional drug transporters (OAT1, OAT3, OCT2, P-gp, MRP2/4, BCRP) for more than 20 passages. Suitable for nephrotoxicity screening, DDI studies, and ADME-tox in early drug discovery. Used in 30+ laboratories worldwide, supported by 90+ peer-reviewed publications. All products available on request – contact us for volumes, documentation, and protocol support.

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