Cell4Pharma

The Human BCRP Vesicle Kit (HEK293 derived) provides ready-to-use inside-out membrane vesicles for ATP-dependent transport studies of the Breast Cancer Resistance Protein (BCRP / ABCG2). Produced by Cell4Pharma from transiently transfected HEK293 cells, each kit contains sufficient material for 100 reactions and is supplied...

Human BSEP Vesicle Kit – Inside-Out Membrane Vesicles for Hepatotoxicity and Cholestasis Risk Assessment The Human BSEP Vesicle Kit (HEK293 derived) provides ready-to-use inside-out membrane vesicles for ATP-dependent transport studies of the Bile Salt Export Pump (BSEP / ABCB11). Each kit contains material for...

Comprehensive Overview of the Human Control Vesicle Kit The Human Control Vesicle Kit (HEK293 derived) provides inside-out membrane vesicles prepared from HEK293 cells transfected with empty vector (no transporter). These matched control vesicles are produced using the identical process as all Cell4Pharma transporter vesicle...

Human MRP1 Vesicle Kit – Inside-Out Membrane Vesicles for Multidrug Resistance and Organic Anion Transport Studies The Human MRP1 Vesicle Kit (HEK293 derived) provides ready-to-use inside-out membrane vesicles for ATP-dependent transport studies of Multidrug Resistance-Associated Protein 1 (MRP1 / ABCC1). Each kit contains material...

Human MRP2 Vesicle Kit – Inside-Out Membrane Vesicles for Biliary Drug Excretion and DDI Studies The Human MRP2 Vesicle Kit (HEK293 derived) provides ready-to-use inside-out membrane vesicles for ATP-dependent transport studies of Multidrug Resistance-Associated Protein 2 (MRP2 / ABCC2). With a guaranteed ATP/AMP ratio...

Human MRP3 Vesicle Kit – Inside-Out Membrane Vesicles for Hepatic Basolateral Efflux and Bile Acid Transport Studies The Human MRP3 Vesicle Kit (HEK293 derived) provides ready-to-use inside-out membrane vesicles for ATP-dependent transport studies of MRP3 (ABCC3). MRP3 is expressed at the basolateral membrane of...

Human MRP4 Vesicle Kit – Inside-Out Membrane Vesicles for Renal Proximal Tubule and Nucleotide Transport Studies The Human MRP4 Vesicle Kit (HEK293 derived) provides ready-to-use inside-out membrane vesicles for ATP-dependent transport studies of MRP4 (ABCC4). MRP4 is expressed in renal proximal tubules, hepatocytes, platelets,...

Human MRP5 Vesicle Kit – Inside-Out Membrane Vesicles for Ubiquitous Organic Anion and Cyclic Nucleotide Transport Studies The Human MRP5 Vesicle Kit (HEK293 derived) provides ready-to-use inside-out membrane vesicles for ATP-dependent transport studies of MRP5 (ABCC5). Unlike other MRPs with organ-specific expression, MRP5 is...

Human MRP8 Vesicle Kit – Inside-Out Membrane Vesicles for Steroid Sulfate, Bile Acid and Nucleoside Analogue Transport Studies The Human MRP8 Vesicle Kit (HEK293 derived) provides ready-to-use inside-out membrane vesicles for ATP-dependent transport studies of MRP8 (ABCC11). MRP8 is expressed in brain, mammary gland,...

Detailed Overview of the Human Pgp Vesicle Kit The Human Pgp Vesicle Kit provides inside-out membrane vesicles isolated from HEK293 cells transiently overexpressing P-glycoprotein (P-gp / MDR1 / ABCB1). P-gp is one of the most clinically relevant drug efflux transporters and is present at...

Comprehensive Overview of the Human Pgp Vesicle Kit The Human Pgp Vesicle Kit with FluoPgp Substrate (HEK293 derived) combines the proven Cell4Pharma Pgp inside-out vesicle system with the proprietary FluoPgp fluorescent probe substrate — eliminating the need for radiolabelled compounds or LC-MS/MS infrastructure. The...