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SeamlessBio rHSA Premium Grade is a high-purity, animal-free recombinant human serum albumin produced in genetically modified rice endosperm cells (Oryza sativa). A three-step chromatography purification process delivers ≥99% purity and ultra-low endotoxin levels (<0.125 EU/mg) — meeting the most demanding quality requirements of serum-free cell culture, ATMP manufacturing, IVD reagent production, biopharmaceutical formulation, and cosmetics.
Structurally identical to native human serum albumin. Free of all blood-derived contaminants, TSE/BSE agents, and human or animal raw materials. Available as lyophilized powder from EU stock.
| Parameter | Specification |
|---|---|
| Expression system | Rice (Oryza sativa) endosperm — 100% animal-free |
| Purity (SDS-PAGE) | ≥99.0% — 3-step chromatography (HYC002M01) |
| Protein content | ≥90.0% |
| Bacterial endotoxins | <0.125 EU/mg (LAL method) |
| Dimer + polymer (non-reducing SDS-PAGE) | Specification >2.0%; typical ≤5.6% |
| pH | 6.0–8.0 |
| Appearance | Light yellow crystalline powder |
| Form | Lyophilized powder |
| Reconstitution | Sterile PBS or 0.9% NaCl; fully soluble within 15 min |
| Storage | 2–8 °C; shelf life 5 years from manufacture |
| TSE/BSE status | TSE/BSE-free — no animal raw materials used |
| Manufacturer | Wuhan Healthgen Biotechnology Corp. (Oryzogen); distributed under SeamlessBio label |
| Regulatory | For Research Use Only (RUO). CoA, CoO and SDS on request. |
| Application | Function of rHSA Premium Grade |
|---|---|
| Serum-free & xeno-free cell culture | Lipid and hormone carrier; protects CHO, HEK293, hybridoma, VERO cells from oxidative stress and shear damage in defined media. |
| CAR-T / NK cell / MSC expansion (ATMP) | Xeno-free supplement meeting GMP-compatible purity and endotoxin requirements for clinical cell therapy manufacturing. |
| IVD reagent manufacturing | Ultra-low endotoxin blocking agent and stabiliser in ELISA kits, lateral flow assays, and immunoassay reagents — minimises background interference. |
| Biopharmaceutical formulation | Stabiliser for therapeutic proteins, vaccines, viral vectors, and antibody-drug conjugates. |
| Cryopreservation | Animal-free replacement for plasma-derived HSA in GMP-compatible freeze media. |
| Cosmetics | High-purity, animal-free protein ingredient for premium skin and dermatological formulations. |
| Grade | Purity | Endotoxin | Best For |
|---|---|---|---|
| rHSA Premium Grade (this product) | ≥99% | <0.125 EU/mg | Cell culture, ATMP, IVD |
| rHSA Economy Grade | 90–99% | <5 EU/mg | IVD, Cosmetics |
| rHSA CHO-Expressed | ≥95% | <1 EU/mg | ADME, drug formulation |
| Advantage | Description |
|---|---|
| ✔ EU warehouse stock | Fast delivery across Germany, Austria, Switzerland and the EU |
| ✔ Direct contact | Speak to a scientist in German or English |
| ✔ Full documentation | CoA, CoO and SDS available for every lot on request |
| ✔ Batch reservation | Reserve a specific lot for your entire project duration |
Prices and pack sizes on request: info@seamlessbio.de | +49 851 37932226
Feedback from our valued business partners
We have been working with Seamless Bio for several large orders, and the service is consistently outstanding. Fast dispatch, careful packaging, and excellent communication make them a trusted supplier for our lab needs.
Seamless Bio always delivers on time with top-quality products. Their team is proactive and helpful, ensuring that every order meets our exact specifications. A true partner in our daily operations.
