Human Serum Heat Inactivated | Mixed Donors | EU/US Origin | sterile filtered

Human Serum for Cell Culture – Heat Inactivated | EU/US Origin

SeamlessBio Human Serum is a high-quality, pooled human serum for cell culture, diagnostics, and biopharmaceutical research. Collected from mixed gender donors at certified EU and US donor centers, each batch is heat inactivated (56 °C, 30 min) and sterile filtered at 0.2 µm to ensure safety, clarity, and reproducibility.

Why Use Heat Inactivated Human Serum?

Heat inactivation at 56 °C for 30 minutes destroys complement proteins that can interfere with cell viability assays, immunological experiments, and sensitive cell-based workflows. It is the preferred format for immunoassays, vaccine development, and primary human cell culture.

Key Specifications

• Origin: EU / US – certified and traceable donor centers
• Donor pool: Mixed gender (male + female) for consistent composition
• Processing: Heat inactivated at 56 °C for 30 min
• Filtration: 0.2 µm sterile filtered
• QC tested: pH, osmolality, total protein, sterility
• Documentation: CoA, COO, MSDS with every order
• Storage: −20 °C | Cold-chain shipping (dry ice)
• Volumes: 100 mL and 500 mL (larger volumes on request)

Applications

• Human and mammalian cell culture (primary cells, immortalized lines)
• Immunoassay and ELISA development
• Complement-sensitive assays and antibody validation
• Vaccine and biologics development
• Cell-based research and diagnostic reagent preparation

Human Serum vs. FBS – Why It Matters

For human cell lines – particularly immune cells, primary cells, and cell therapy applications – human serum is increasingly preferred over fetal bovine serum (FBS). It eliminates the risk of xenogenic immune reactions, supports more physiologically relevant conditions, and is aligned with EMA guidance (EMA/410/01) for cell therapy manufacturing.

Also Available

• Human Serum – Gamma Irradiated
• Human Plasma Bags – multiple anticoagulants
• Fetal Bovine Serum (FBS) – Heat Inactivated

Frequently Asked Questions

What is the difference between heat inactivated and gamma irradiated human serum?

Heat inactivation destroys complement proteins at 56 °C. Gamma irradiation provides enhanced biosafety with broader pathogen reduction while preserving growth factors. Choose based on your assay sensitivity and biosafety requirements.

Is this serum suitable for GMP manufacturing?

This product is supplied as RUO (Research Use Only). GMP-grade material is available on request with full documentation. Contact info@seamlessbio.de for details.

Can I reserve a specific batch?

Yes – batch reservation is available for up to 6 weeks with free warehousing and scheduled delivery. Request via our contact form.

What documentation is included?

Every order includes a Certificate of Analysis (CoA), Certificate of Origin (COO), and Safety Data Sheet (MSDS).